The role of microhomology in genomic structural variation.
Publication Date: 2014 Feb 3 PMID: 24503142Authors: Ottaviani, D. - Lecain, M. - Sheer, D.Journal: Trends GenetGenomic structural variation, which can be defined as differences in the copy number,...
View ArticleHP1a: a structural chromosomal protein regulating transcription.
Publication Date: 2014 Feb 17 PMID: 24555990Authors: Eissenberg, J. C. - Elgin, S. C.Journal: Trends GenetHeterochromatin protein 1 (HP1a in Drosophila) is a conserved eukaryotic chromosomal protein...
View ArticleCRISPR-based technologies: prokaryotic defense weapons repurposed.
Publication Date: 2014 Feb 17 PMID: 24555991Authors: Terns, R. M. - Terns, M. P.Journal: Trends GenetTo combat potentially deadly viral infections, prokaryotic microbes enlist small RNA-based adaptive...
View ArticleSystemic DNA damage responses: organismal adaptations to genome instability.
Publication Date: 2014 Mar PMID: 24439457Authors: Ermolaeva, M. A. - Schumacher, B.Journal: Trends GenetDNA damage checkpoints are important tumor-suppressor mechanisms that halt cell cycle progression...
View ArticleThe four dimensions of noncoding RNA conservation.
Publication Date: 2014 Mar 6 PMID: 24613441Authors: Diederichs, S.Journal: Trends GenetEvolutionary conservation is widely used as an indicator of the functional significance of newly discovered genes....
View ArticleExplaining additional genetic variation in complex traits.
Publication Date: 2014 Mar 11 PMID: 24629526Authors: Robinson, M. R. - Wray, N. R. - Visscher, P. M.Journal: Trends GenetGenome-wide association studies (GWAS) have provided valuable insights into the...
View ArticleModeling genomic regulatory networks with big data.
Publication Date: 2014 Mar 12 PMID: 24630831Authors: Bolouri, H.Journal: Trends GenetHigh-throughput sequencing, large-scale data generation projects, and web-based cloud computing are changing how...
View ArticleCatch and release: how do kinetochores hook the right microtubules during...
Publication Date: 2014 Mar 13 PMID: 24631209Authors: Sarangapani, K. K. - Asbury, C. L.Journal: Trends GenetSport fishermen keep tension on their lines to prevent hooked fish from releasing. A...
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